(04-09-06) Nutritional status, protein intake and progression of renal failure in children.

Sahpazova E, Kuzmanovska D, Todorovska L, Bogdanovska A.

Pediatric Clinic, Division of Nephrology, Medical Faculty, Vodnjanska 17, 1000, Skopje R., Macedonia, [email protected].

Nutritional status and progression of renal failure in 35 children (22 males and 13 females; mean age: 8.85+/-4.13 years) with moderate renal failure were followed for 2 years. All children were on an "ad libidum" diet. Protein intake was determined by a minimum of two dietary diaries kept by the parents and the appearance of urea nitrogen. The children were divided into two groups according to their protein intake: Group 1 - sub-optimal intake (46% of the children, all with significantly lower protein intake); Group 2 - adequate protein intake. The mean protein intake (expressed as a percentage of the WHO recommendations) based on the diets of the patients was 94.79% in Group 1 children and 175.45% in Group 2 children (p<0.05). All patients had a calorie intake of at least 80% of the WHO recommendations. Nutritional status was determined by anthropometric measurements expressed as a standard deviation score. There was no significant anthropometric or biochemical evidence of malnutrition in children with moderate chronic renal failure (CRF). The glomerular filtration rate (GFR) in patients with a sub-optimal intake of protein was -5.41+/-2.87 ml/2 year versus-9.53+/-8.61 ml/2 year in the normal protein intake group. There was no correlation between protein intake, nutritional status and progression of renal failure in children with moderate CRF within the 2-year study period.

PMID: 16941144 [PubMed - as supplied by publisher]

Source: Pediatr Nephrol. 2006 Aug 29; [Epub ahead of print]

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